500
Participants
Start Date
July 31, 2009
Primary Completion Date
July 31, 2015
Study Completion Date
January 31, 2016
Alteplase
1.0 mg of alteplase will be administered via the intraventricular catheter every 8 hours for up to 12 doses
Normal saline
1 ml of normal saline will be administered via the intraventricular catheter every 8 hours for up to 12 doses
Honved Korhaz, Budapest
University of Debrecen, Debrecen
University of Szeged, Szeged
University of Pecs, Pécs
Mount Sinai Hospital, New York
Columbia University, New York
Northshore University Hospital Long Island, Manhasset
SUNY Upstate Medical Center, Syracuse
University of Buffalo, Buffalo
Allegheny General Hospital, Pittsburgh
University of Pittsburgh Medical Center, Pittsburgh
Penn State Hershey Medical Center, Hershey
Abington Memorial Hospital, Abington
Thomas Jefferson University Hospital, Philadelphia
Temple University Hospital, Philadelphia
Albert Einstein Medical Center, Philadelphia
Georgetown University, Washington D.C.
University of Maryland, Baltimore
Johns Hopkins University, Baltimore
Virginia Commonwealth University, Richmond
Wake Forest University, Winston-Salem
Medical University of South Carolina, Charleston
Rambam Medical Center, Haifa
Mayo Clinic, Jacksonville, Jacksonville
University of South Florida, Tampa
Intercoastal Medical Center, Sarasota
University of Alabama at Birmingham, Birmingham
Vanderbilt, Nashville
Ohio State University Medical Center, Columbus
Case-Western Reserve University Hospital, Cleveland
University of Cincinnati, Cincinnati
Henry Ford Health System, Detroit
Ruan Neurology Clinical and Research Center, Des Moines
University of Iowa, Iowa City
Chaim Sheba Medical Center, Ramat Gan
Medical College of Wisconsin, Milwaukee
Rush University, Chicago
University of Illinois at Chicago, Chicago
University of Chicago, Chicago
St. Louis University, St Louis
St. Luke's Brain and Stroke Institute, Kansas City
Sourasky Medical Center, Tel Aviv
Springfield Neurological and Spine Institute, Springfield
Kansas University Medical Center, Kansas City
University of Heidelberg, Heidelberg
University of Tubingen, Tübingen
University of Texas, Southwestern, Dallas, Dallas
University of Texas, Houston, Houston
University of Texas, San Antonio, San Antonio
University of Utah, Salt Lake City
Mayo Clinic, Arizona, Phoenix
Cedars-Sinai Medical Center, Los Angeles
University of Southern California - Keck School of Medicine, Los Angeles
University of California Los Angeles, Los Angeles
University of Erlangen, Erlangen
Hadassah Hebrew University Hospital, Jerusalem
Stanford University, Palo Alto
Providence Stroke Center, Portland
Hospital Sao Jose, Joinville, Joinville
Hartford Hospital, Hartford
Yale University, New Haven
Cooper University Hospital, Camden
New Jersey Neuroscience Institute at JFK, Edison
Maine Medical Center, Portland
Hospital de Clinicas de Porto Alegre, Porto Alegre
Hospital de Pronto Socorro de Porto Alegre, Porto Alegre
University Hospital, Inselpital, Bern, Bern
Hospital de Clinicas de Ribeirao Preto, Ribeirão Preto
Hospital Sao Paulo Universidade Federal de Sao Paulo / UNIFESP, São Paulo
University of Alberta, Edmonton
Montreal Neurological Institute at McGill University, Montreal
University of Halle, Halle
University of Leipzig, Leipzig
University of Mainz, Mainz
Bellvitge Hospital, Barcelona
Hospital de la Santa Creu i Sant Pau, Barcelona
Vall d'Hebron University Hospital, Barcelona
University of Zurich, Zurich
Salford Royal NHS Foundation Trust, Salford
Newcastle General Hospital, Newcastle upon Tyne
University of Southampton Hospital, Southampton
Collaborators (2)
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Genentech, Inc.
INDUSTRY
Emissary International LLC
INDUSTRY
Johns Hopkins University
OTHER