T-Cat Laser & Cross-linking for Keratoconus

NACompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

October 31, 2008

Primary Completion Date

October 31, 2010

Study Completion Date

October 31, 2010

Conditions
KeratoconusPellucid Marginal Degeneration
Interventions
PROCEDURE

Excimer laser ablation, and collagen cross-linking

Surgery is performed with topical anaesthesia. The central corneal epithelium is removed. Excimer laser ablation is applied (typically 15-30 seconds). Residual bed thickness is checked with an ultrasonic pachymeter. Topical application of riboflavin 0.1% in dextran is commenced at 5 minute intervals. When an adequate saturation of the anterior chamber with riboflavin has been achieved, cross-linking treatment will proceed. Output from the UV light generating equipment is measured with a UV light meter and set at 3mW/cm². Thirty minutes of treatment is given, interrupted at five minute intervals by the application of more topical riboflavin drops. Finally the eye has a bandage soft contact lens placed, with preservative free topical antibiotic, steroid, and cycloplegic drop application.

Trial Locations (1)

SW17 0QT

Moorfields Eye Department at St George's Hospital, London

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Accuvision Laser Eye Clinics

OTHER

collaborator

Carleton Optical Equipment Ltd.

INDUSTRY

collaborator

Bon Optics

OTHER

collaborator

Sooft Italia

INDUSTRY

lead

Moorfields Eye Hospital NHS Foundation Trust

OTHER