15
Participants
Start Date
October 31, 2008
Primary Completion Date
October 31, 2010
Study Completion Date
October 31, 2010
Excimer laser ablation, and collagen cross-linking
Surgery is performed with topical anaesthesia. The central corneal epithelium is removed. Excimer laser ablation is applied (typically 15-30 seconds). Residual bed thickness is checked with an ultrasonic pachymeter. Topical application of riboflavin 0.1% in dextran is commenced at 5 minute intervals. When an adequate saturation of the anterior chamber with riboflavin has been achieved, cross-linking treatment will proceed. Output from the UV light generating equipment is measured with a UV light meter and set at 3mW/cm². Thirty minutes of treatment is given, interrupted at five minute intervals by the application of more topical riboflavin drops. Finally the eye has a bandage soft contact lens placed, with preservative free topical antibiotic, steroid, and cycloplegic drop application.
Moorfields Eye Department at St George's Hospital, London
Collaborators (1)
Accuvision Laser Eye Clinics
OTHER
Carleton Optical Equipment Ltd.
INDUSTRY
Bon Optics
OTHER
Sooft Italia
INDUSTRY
Moorfields Eye Hospital NHS Foundation Trust
OTHER