NCT00774098View on ClinicalTrials.gov

Improving Glycogen Liver Content Will Improve Post-operative Liver Function in Patients Undergoing Major Liver Resections

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

January 31, 2007

Primary Completion Date

September 30, 2009

Study Completion Date

September 30, 2009

Conditions
Liver Function
Interventions
DRUG

dextrose 10% (D10W ®) infusion

Started at 8pm the day before surgery until the procedure begins

DRUG

hyperinsulinemic normoglycemic clamp

Started as the procedure begins, decreased at the end of the procedure and continued until 16 hours postoperatively

DIETARY_SUPPLEMENT

high calorie diet 35 kcal/kg

High Calorie meals start the day before the surgery and are given 5 hours apart. The last meal is given at 7 pm the day before surgery

DRUG

Intravenous normal saline (NS 0.9)

Intravenous normal saline (NS 0.9) started just before induction, and titrated to hemodynamic parameters and urine output

Trial Locations (1)

H3A1A1

Royal Victoria Hospital, Montreal

All Listed Sponsors
lead

McGill University Health Centre/Research Institute of the McGill University Health Centre

OTHER

NCT00774098 - Improving Glycogen Liver Content Will Improve Post-operative Liver Function in Patients Undergoing Major Liver Resections | Biotech Hunter | Biotech Hunter