A Phase Ib Study of ISF35 in Combination With Chemotherapy (FCR) in Subjects With Relapsed, Refractory, and/or 17p- CLL

PHASE1CompletedINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

September 30, 2008

Primary Completion Date

April 30, 2011

Study Completion Date

April 30, 2013

Conditions
Chronic Lymphocytic Leukemia
Interventions
BIOLOGICAL

ISF35

Subjects participating in this study will receive a course of three infusions of 3x10\^8 ISF35-transduced cells at periods of not less than 14 days apart followed by a standard regimen of three cycles of fludarabine, cyclophosphamide and rituximab (FCR) at monthly intervals.

Trial Locations (1)

92093

University of California, San Diego Moores Cancer Center, San Diego

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

The Leukemia and Lymphoma Society

OTHER

collaborator

University of California, San Diego

OTHER

lead

Memgen, LLC

INDUSTRY

NCT00772486 - A Phase Ib Study of ISF35 in Combination With Chemotherapy (FCR) in Subjects With Relapsed, Refractory, and/or 17p- CLL | Biotech Hunter | Biotech Hunter