Cancer Immunotherapy
Total Trials
8
As Lead Sponsor
3
As Collaborator
5
Total Enrollment
93
NCT00850057
Pharmacodynamic (PD) Study of Intranodal Adenovirus-CD154 (Ad-ISF35) in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
Phase: Phase 1
Role: Collaborator
Start: Feb 28, 2006
Completion: Oct 31, 2009
NCT00779883
A Phase I Trial of Autologous CLL B Cells Transduced to Express Chimeric CD154 (ISF35)
Role: Lead Sponsor
Start: Jun 30, 2006
Completion: Mar 31, 2008
NCT00783588
A Phase I Extension Trial of Repeated Infusions of ISF35
Start: May 31, 2007
Completion: Sep 30, 2008
NCT00772486
A Phase Ib Study of ISF35 in Combination With Chemotherapy (FCR) in Subjects With Relapsed, Refractory, and/or 17p- CLL
Start: Sep 30, 2008
Completion: Apr 30, 2013
NCT00849524
Study of Repeat Intranodal Injection of Memgen's Cancer Vaccine, Ad-ISF35, in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
Phase: Phase 2
Start: Jan 31, 2009
Completion: Jul 31, 2014
NCT00942409
Study of Repeat Intranodal Injections of Ad-ISF35
Start: Jun 30, 2009
NCT02719015
Dose Escalation and Cohort Expansion of Safety and Tolerability Study of Intratumoral rAd.CD40L (ISF35) in Combination of Systemic Pembrolizumab in Patients With Refractory Metastatic Melanoma
Phase: Phase 1/2
Start: Mar 31, 2018
Completion: Mar 31, 2022
NCT06693297
Immediate Versus Conventional Loading of Early Placed Dental Implant Supporting Single Crowns
Phase: N/A
Start: Sep 25, 2024
Completion: Sep 30, 2026
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