Study of IMC-3G3 in Patients With Tumors That Are Not Responding to Standard Therapies or No Therapy is Available

PHASE1CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

December 31, 2006

Primary Completion Date

March 31, 2009

Study Completion Date

January 31, 2010

Conditions
Solid Tumors
Interventions
BIOLOGICAL

IMC-3G3

Intravenously, once every week for Cohorts 1 through 3 and once every other week for Cohorts 4 and 5. Starting dose will be 4mg/kg in Cohort 1, with dose doubling between cohorts. Dose escalation of 100% (2 x previous dose) Dose escalation increment reduced to 33% (1.33 x previous dose). Cohorts 4 and 5 will receive 15mg/kg and 20mg/kg, intravenously, once every other week.

Trial Locations (2)

46282

ImClone Investigational Site, Indianapolis

77030

ImClone Investigational Site, Houston

All Listed Sponsors
lead

Eli Lilly and Company

INDUSTRY

NCT00768391 - Study of IMC-3G3 in Patients With Tumors That Are Not Responding to Standard Therapies or No Therapy is Available | Biotech Hunter | Biotech Hunter