(ARTEMIS-IPF) Randomized, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF

PHASE3TerminatedINTERVENTIONAL
Enrollment

494

Participants

Timeline

Start Date

December 31, 2008

Primary Completion Date

February 28, 2011

Study Completion Date

February 28, 2011

Conditions
Idiopathic Pulmonary Fibrosis
Interventions
DRUG

Ambrisentan

Ambrisentan (5mg or 10 mg tablet) was administered orally once daily.

DRUG

Placebo

Placebo to match ambrisentan was administered orally once daily.

Trial Locations (185)

7

Dublin

1011

Lausanne

1070

Anderlecht

1090

Vienna

1200

Brussels

2010

Darlinghurst

2139

Concord

3000

Leuven

3010

Bern

3050

Parkville

3181

Prahran

4020

Linz

4031

Basel

4032

Chermside

5011

Woodville

5530

Yvoir

6000

Perth

6020

Innsbruck

7000

Hobart

8036

Graz

10029

New York

10032

Columbia University Medical Center, New York

10043

Torino

10117

Berlin

11009

Cadiz

11040

New Hyde Park

11501

Winthrop University Hospital, Mineola

12205

Pulmonary And Critical Care Services, P.C., Albany

13009

Marseille

14080

Mexico City, DF

15212

Pittsburgh

15213

University of Pittsburgh, Pittsburgh

19104

University of Pennsylvania Health Systems, Philadelphia

19140

Philadelphia

19611

The Reading Hospital and Medical Center, Reading

19713

Newark

20123

Milan

20132

Milan

21201

Baltimore

21205

Baltimore

22042

Falls Church

22908

Charlottesville

24080

Complejo Asistencial Universitario de León, León

24501

Lynchburg

27710

Duke University Medical Center, Durham

28007

Madrid

28223

Pozuelo de Alarcón

29072

Lexington

29303

Spartanburg

29425

Medical University of South Carolina, Charleston

30322

Emory University, Atlanta

31096

Haifa

33006

Oviedo

33136

University of Miami Miller School of Medicine, Miami

33604

Pessac

33606

Tampa

33756

Bay Area Chest Physicians, Clearwater

34295

Montpellier

34362

Haifa

35033

Rennes

35128

Padua

35294

University of Alabama at Birmingham Hospital, Birmingham

36071

Pontevedra

37044

Tours

37232

Nashville

40202

Kentuckiana Pulmonary Association, Louisville

Louisville

41011

Hospital Virgen del Rocio, Seville

41100

Modena

43215

Columbus

44670

Guadalajara

44795

The Cleveland Clinic Foundation, Cleveland

45200

Zapopan, Jalisco

45267

Cincinnati

47100

Forlì

48109

Ann Arbor

49100

Petah Tikva

51503

Council Bluffs

52621

Tel Litwinsky

52763

Huixquilucan Edo. de Mexico

53100

Siena

55905

Mayo Clinic, Rochester

59037

Lille

60637

University of Chicago, Chicago

63017

Saint Lukes Foundation, Chesterfield

64239

Tel Aviv

64460

Monterrey

64718

Monterrey

69126

Heidelberg

75015

Paris

75018

Paris

75069

McKinney

76100

Rehovot

77030

Houston

78306

Ashkelon

79106

Freiburg im Breisgau

80131

Napoli

80206

National Jewish Medical And Research Center, Denver

81377

München

84101

Beersheba

84108

Salt Lake City

84604

Provo

85006

Pulmonary Associates, Phoenix

85258

Scottsdale

90095

David Geffen School of Medicine at UCLA(Harbor-UCLA Medical Center), Los Angeles

90127

Palermo

91031

Jerusalem

91120

Jerusalem

93093

Donaustauf

94143

San Francisco

94305

Stanford University, Stanford

95123

Catania

95817

University of California, Davis, Sacramento

97220

The Oregon Clinic, P.C., Portland

98195

Seattle

98201

Everett

2352499

Valparaíso

4270918

Talcahuano

7500691

Santiago

92103-8373

San Diego

02115

Boston

02215

Boston

03756

Dartmouth Medical School, Lebanon

08903

New Brunswick

08854

Piscataway

07091

Pulmonary & Allergy Associates, Summit

B7602DCK

Mar del Plata

Mar Del Plata, Buenos Aires

C1181ACH

Buenos Aires

C1280AEB

Buenos Aires

C1425DES

Buenos Aires

T4000HXU

San Miguel de Tucumán

04023-062

São Paulo

30430-1

Belo Horizonte

88040-970

Florianópolis

74605-050

Goiânia

90035-074

Porto Alegre

90610-000

Porto Alegre

91350-200

Porto Alegre

21949-900

Rio de Janeiro

09060-650

Santo André

T1Y6J4

Calgary

T6G 2C8

Edmondton

V5Z 1M9

Vancouver

V6Z 1YP

Vancouver

A1B 3V6

St. John's

H2W1T8

Montreal

G1V 4G5

Sainte-Foy

M4X1104

Toronto

Unknown

Bogotá

Floridablanca

625-00

Brno

500 05

Hradec Králové

586 33

Jihlava

460 63

Liberec

775-20

Olomouc

305 99

Pilsen

06002

Nice

D-13125

Berlin

01640

Coswig

D-45239

Essen

D-17475

Greifswald

D-74245

Löwenstein

00133

Roma

7609 PP

Almelo

Callao 02

Callao

L31

Lima

L33

Lima

Lima 01

Lima

Lima 27

Lima

Lima 41

Lima

85-681

Bydgoszcz

90-153

Lodz

08916

Badalona

08036

Barcelona

S10 2JF

Sheffield

KT16 0PZ

Chertsey

CB2 2QQ

Cambridge

CM1 7ET

Chelmsford

EH16 4SA

Edinburgh

G4 0SF

Glasgow

L9 7AL

Liverpool

NW1 2PG

London

SW3 6NP

London

M23 9LT

Mancesheter

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Gilead Sciences

INDUSTRY