Evaluation of Intravenous Cardene(Nicardipine)and Labetalol Use in the Emergency Department

PHASE4CompletedINTERVENTIONAL
Enrollment

226

Participants

Timeline

Start Date

October 31, 2008

Primary Completion Date

January 31, 2010

Study Completion Date

January 31, 2010

Conditions
Hypertensive Urgency
Interventions
DRUG

nicardipine intravenous

nicardipine intravenous 5 mg/hour titrated every 5 minutes by 2.5 mg/hour until target systolic blood pressure range (TSBPR) is reached or maximum dose of 15 mg/hour is achieved.Following achievement of target systolic blood pressure range the infusion rate should be decreased to 3 mg/hour

DRUG

Labetalol

Labetalol: bolus therapy to start at 20 mg intravenous injection over 2 minutes, may repeat 20mg, 40mg or 80mg injections every 10 minutes until target systolic blood pressure range(TSBPR)is reached or a maximum of 300 mg is injected.

Trial Locations (2)

44122

Cleveland Clinic, Cleveland

Unknown

University of Texas Health Science Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

EKR Therapeutics, Inc

INDUSTRY

lead

The Cleveland Clinic

OTHER

NCT00765648 - Evaluation of Intravenous Cardene(Nicardipine)and Labetalol Use in the Emergency Department | Biotech Hunter | Biotech Hunter