Study of the Effect of Dipyrone, Ibuprofen, Paracetamol and Parecoxib on the Platelet Aggregation in Analgetic Dosages

Dipyrone is given in the operation room with 2,5 g intravenously, followed by an oral regime of 4x1g on the ward

Ibuprofen is given orally 600mg in the Post Anesthesia Care Unit, followed by an oral regime of 800mg twice a day

Acetaminophen is given 1g intravenously in the Operation room, followed by an oral regime of 1g fourth a day

Acetaminophen is given 1g intravenously in the operation room, followed by 1g orally fourth a day

40mg Parecoxib are given intravenously in the operation room, followed by 40mg of Valdecoxib orally twice a day

Blood samples for aggregometry are taken before induction of anesthesia, 1h after first drug intake, 4hs and 24hs after first intake