Endothelial Function in Lower Extremity Bypass Grafts

NACompletedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

April 30, 2006

Primary Completion Date

December 31, 2009

Study Completion Date

December 31, 2009

Conditions
Peripheral Arterial Disease
Interventions
DRUG

L-N^G monomethyl arginine (L-NMMA)

L-NMMA was infused at a dose of 1 mg/kg over 10 minutes to competitively inhibit the production of nitric oxide. Ultrasound imaging of the saphenous vein \[arterial\] bypass at baseline, and following an ischemic stimulus, administration of sublingual nitroglycerin, and intravenous administration of L-NMMA.

Trial Locations (1)

02115

Brigham and Women's Hospital, Boston

All Listed Sponsors
lead

Brigham and Women's Hospital

OTHER

NCT00759707 - Endothelial Function in Lower Extremity Bypass Grafts | Biotech Hunter | Biotech Hunter