NCT00754247View on ClinicalTrials.gov

A Randomized Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treatment of Keloids and Hypertrophic Scars

PHASE4CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

March 31, 2006

Primary Completion Date

February 29, 2008

Study Completion Date

February 29, 2008

Conditions
KeloidHypertrophic ScarCicatrix, Hypertrophic
Interventions
DRUG

0.5% hydrocortisone, silicone, vitamin E lotion

0.5% hydrocortisone, silicone, vitamin E lotion will be applied topically to cover the selected scar twice daily for 16 weeks. The lesion will be cleansed with soap and water and dried thoroughly. The medication will be applied with a brush and allow it to dry for one minute before contact with clothing.

DRUG

Onion extract gel

Onion extract gel is applied and massaged into the selected scar 3 to 4 times daily according to product instructions for 16 weeks.

DRUG

Cetearyl alcohol lotion

Placebo is cetearyl alcohol lotion with no steroids, silicone, vitamin E, or onion extract and will be applied 2 times a day to the lesion.

Trial Locations (1)

33136

University of Miami Skin Research Group Office, Miami

All Listed Sponsors
lead

University of Miami

OTHER

NCT00754247 - A Randomized Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treatment of Keloids and Hypertrophic Scars | Biotech Hunter | Biotech Hunter