AScVS and/ or Prazosin for Scorpion Envenomation

PHASE3CompletedINTERVENTIONAL
Enrollment

81

Participants

Timeline

Start Date

September 30, 2006

Primary Completion Date

December 31, 2007

Study Completion Date

December 31, 2007

Conditions
Scorpion Envenomation
Interventions
DRUG

Antiscorpion venom serum(AScVS).

"AScVS therapy group~If the score is 5 and if the patient belongs to pediatric group(\>12-14): 1 vial AScVS as i.v. slow bolus after test dose If the score is 5 and if the patient is adult: 2 vials of AScVS as i.v. slow bolus after test dose. For injection, 1 vial will be dissolved in 10 ml distilled water and given over a period of 4 to 5 minutes.~According to the scores 1 vial for pediatric and 2 vials for adult patient will be increased as shown below:~Vials of AScVS Composite score Child Adult 5-10 2 4 \> 10-15 3 6 \>15- 21 4 8"

DRUG

T.Prazosin

Prazosin therapy Prazosin (30 micrograms/Kg/dose): 500 micrograms for pediatric patient, and 1mg for adult patients) will be given every 3 hourly orally till complete recovery.

DRUG

AScVS + Prazosin

Combination AScVS and Prazosin therapy In this group, AScVS therapy will be given as mentioned in AScVS therapy group and in addition, prazosin(500 micrograms for pediatric patient and 1mg for adult patients,30 micrograms/Kg/dose) every 3 hourly will be given.

Trial Locations (5)

402104

Mangaon cottage hospital, Mangaon., Dist. Raigad.

415605

Kushte Hospital, Chiplūn

Natu Hospital, Chiplūn

Sane Hospital, Chiplūn

415702

Vijayshree Hospital,At & Po.Umroli,Tal. Chiplun., Dist. Ratnagiri.

All Listed Sponsors
lead

Haffkine Bio-Pharmaceutical Corporation Ltd.

INDUSTRY