Stereotactic Body Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

February 28, 2009

Primary Completion Date

September 30, 2014

Study Completion Date

May 20, 2022

Conditions
Lung Cancer
Interventions
RADIATION

SBRT 40.0 Gy

SBRT delivered in 5 fractions of 8.0 Gy/fraction over 1.5 to 2 weeks for a total of 40.0 Gy

RADIATION

SBRT 42.5 Gy

SBRT delivered in 5 fractions of 8.5 Gy/fraction over 1.5 to 2 weeks for a total of 42.5 Gy

RADIATION

SBRT 45.0 Gy

SBRT delivered in 5 fractions of 9.0 Gy/fraction over 1.5 to 2 weeks for a total of 45.0 Gy

RADIATION

SBRT 47.5 Gy

SBRT delivered in 5 fractions of 9.5 Gy/fraction over 1.5 to 2 weeks for a total of 47.5 Gy

RADIATION

SBRT 50.0 Gy

SBRT delivered in 5 fractions of 10.0 Gy/fraction over 1.5 to 2 weeks for a total of 50.0 Gy

RADIATION

SBRT 52.5 Gy

SBRT delivered in 5 fractions of 10.5 Gy/fraction over 1.5 to 2 weeks for a total of 52.5 Gy

RADIATION

SBRT 55.0 Gy

SBRT delivered in 5 fractions of 11.0 Gy/fraction over 1.5 to 2 weeks for a total of 55.0 Gy

RADIATION

SBRT 57.5 Gy

SBRT delivered in 5 fractions of 11.5 Gy/fraction over 1.5 to 2 weeks for a total of 57.5 Gy

RADIATION

SBRT 60.0 Gy

SBRT delivered in 5 fractions of 12.0 Gy/fraction over 1.5 to 2 weeks for a total of 60.0 Gy

Trial Locations (58)

10025

St. Luke's - Roosevelt Hospital Center - St.Luke's Division, New York

10032

Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, New York

14642

James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester

18301

Dale and Frances Hughes Cancer Center at Pocono Medical Center, East Stroudsburg

19001

Rosenfeld Cancer Center at Abington Memorial Hospital, Abington

19096

Lankenau Cancer Center at Lankenau Hospital, Wynnewood

19114

Frankford Hospital Cancer Center - Torresdale Campus, Philadelphia

19141

Albert Einstein Cancer Center, Philadelphia

19713

CCOP - Christiana Care Health Services, Newark

21201

Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore

23507

Sentara Cancer Institute at Sentara Norfolk General Hospital, Norfolk

32207

Baptist Cancer Institute - Jacksonville, Jacksonville

32806

M.D. Anderson Cancer Center at Orlando, Orlando

33140

CCOP - Mount Sinai Medical Center, Miami Beach

40207

Norton Suburban Hospital, Louisville

43560

Flower Hospital Cancer Center, Sylvania

45267

Charles M. Barrett Cancer Center at University Hospital, Cincinnati

48073

William Beaumont Hospital - Royal Oak Campus, Royal Oak

48202

Josephine Ford Cancer Center at Henry Ford Hospital, Detroit

48532

McLaren Cancer Institute, Flint

49503

Butterworth Hospital at Spectrum Health, Grand Rapids

Lacks Cancer Center at Saint Mary's Health Care, Grand Rapids

53226

Medical College of Wisconsin Cancer Center, Milwaukee

53295

Veterans Affairs Medical Center - Milwaukee, Milwaukee

55101

Regions Hospital Cancer Care Center, Saint Paul

55407

Virginia Piper Cancer Institute at Abbott - Northwestern Hospital, Minneapolis

55432

Mercy and Unity Cancer Center at Unity Hospital, Fridley

55433

Mercy and Unity Cancer Center at Mercy Hospital, Coon Rapids

55905

Mayo Clinic Cancer Center, Rochester

61637

OSF St. Francis Medical Center, Peoria

63110

Saint Louis University Cancer Center, St Louis

66208

CCOP - Kansas City, Prairie Village

75390

Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas

85381

Arizona Center for Cancer Care - Peoria, Peoria

90048

Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, Los Angeles

91505

Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center, Burbank

94115

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco

95608

Mercy Cancer Center at Mercy San Juan Medical Center, Carmichael

95682

Radiation Oncology Centers - Cameron Park, Cameron Park

95817

University of California Davis Cancer Center, Sacramento

98195

University Cancer Center at University of Washington Medical Center, Seattle

98225

St. Joseph Cancer Center, Bellingham

85259-5499

Mayo Clinic Scottsdale, Scottsdale

06050

George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus, New Britain

40536-0093

Lucille P. Markey Cancer Center at University of Kentucky, Lexington

71315-3198

Tulane Cancer Center Office of Clinical Research, Alexandria

04074

Maine Center for Cancer Medicine and Blood Disorders - Scarborough, Scarborough

03756-0002

Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon

08054

Cooper CyberKnife Center, Mount Laurel

07871

Frederick R. and Betty M. Smith Cancer Treatment Center, Sparta

14263-0001

Roswell Park Cancer Institute, Buffalo

27157-1096

Wake Forest University Comprehensive Cancer Center, Winston-Salem

44309-2090

Summa Center for Cancer Care at Akron City Hospital, Akron

44106-5065

Case Comprehensive Cancer Center, Cleveland

43210-1240

Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center, Columbus

17033-0850

Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center, Hershey

19612-6052

McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center, Reading

M5G 2M9

Princess Margaret Hospital, Toronto

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

NRG Oncology

OTHER

lead

Radiation Therapy Oncology Group

NETWORK

NCT00750269 - Stereotactic Body Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer | Biotech Hunter | Biotech Hunter