30
Participants
Start Date
July 31, 2005
Primary Completion Date
June 30, 2006
Study Completion Date
June 30, 2008
intramyocardial bone marrow stem cells implantation
"Control group: the patients will be monitored with regular medical visits. Echocardiography: baseline,3,6,9 months. Cardiac NMR at baseline, 3 and 9 months.~Interventional group: Bone-marrow was collected from in the anterior-superior iliac crest and mononuclear stem cells were isolated by centrifugation in the density rate Ficoll-Hypaque 1.077 media. Technique - The approach was through a left mini-thoracotomy. Twenty small injections of cellular suspension were directly made through a 21F butterfly needle(total=5ml), in the anterior, lateral, posterior and apical faces of the LV ((average 9.6±2.6 x 10\[7\] cells). After the procedure, the patients were kept in the p.o. for a minimum period of 24hrs. They were released from the hospital in a period that varied from 5-7 days."
Institute of Cardiology of Rio Grande do Sul / FUC, Porto Alegre
Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil
OTHER
Conselho Nacional de Desenvolvimento Científico e Tecnológico
OTHER_GOV
Instituto de Cardiologia do Rio Grande do Sul
OTHER