The Acetylcysteine for Contrast-Induced Nephropathy Trial

PHASE3CompletedINTERVENTIONAL
Enrollment

2,300

Participants

Timeline

Start Date

August 31, 2008

Primary Completion Date

July 31, 2010

Study Completion Date

July 31, 2010

Conditions
Acute Kidney Failure
Interventions
DRUG

Acetylcysteine

Acetylcysteine: 1200 mg every 12 hours for a total of 4 doses. Treatment is to be started 12 hours before angiography, that is, two doses should be administered before it. When this is not achievable, at least one dose should be administered before angiography.

DRUG

Placebo

Placebo of Acetylcysteine: every 12 hours PO, for a total of 4 doses. Treatment is to be started 12 hours before angiography, that is, two doses should be administered before it. When this is not achievable, at least one dose should be administered before angiography.

Trial Locations (1)

04004030

Hospital do Coração, São Paulo

Sponsors
All Listed Sponsors
collaborator

Medley Pharmaceutical Industry SA

UNKNOWN

lead

Hospital do Coracao

OTHER