NCT00724386 - Concomitant Chemoradiotherapy With Weekly Paclitaxel and Vinorelbine and Granulocyte Colony Stimulating Factor (GCSF) Support in Patients With Advanced Breast Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

June 30, 1999

Primary Completion Date

October 31, 2005

Study Completion Date

November 30, 2012

Conditions

Breast Cancer

Interventions

DRUG

Paclitaxel

1-hour IV infusion once weekly for 12 to 14 weeks

DRUG

Vinorelbine

escalating doses administered intravenously over 6-10 minutes for 12-14 weeks

DRUG

Filgrastim

"daily injections for 6 days beginning on day 2 of second week on study and then every other week (weeks 2, 4, 6, 8, 12).~For the final dose cohort, administration on chemotherapy only weeks, only if dose reduction or dose delay required by subject"

RADIATION

Radiation

Radiotherapy for 5 consecutive days every other week (weeks 1, 3, 5, 7, 9, 11, 13)starting on same day as first dose of protocol chemotherapy

Trial Locations (1)

60637

University of Chicago, Chicago