22
Participants
Start Date
May 31, 2006
Primary Completion Date
November 30, 2007
Study Completion Date
December 31, 2007
BQ-123 (selective endothelin A receptor antagonist)
Single dose of BQ-123 given at a dose of 1000 nmol/min for 15 min intravenously.
0.9 % saline
Single 15ml 0.9% saline infused for 15 mins as placebo control
Nifedipine
Single dose of nifedipine 10 mg given orally as active control
Clinical Research Centre, Western General Hospital, Edinburgh
British Heart Foundation
OTHER
University of Edinburgh
OTHER