Effect of Aprepitant on Cyclophosphamide Pharmacokinetics in Patients With Breast Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

August 31, 2005

Primary Completion Date

October 31, 2010

Study Completion Date

October 31, 2010

Conditions
Breast CancerNausea and Vomiting
Interventions
DRUG

aprepitant

Given orally

DRUG

cyclophosphamide

Given IV

OTHER

placebo

Given orally

Trial Locations (1)

27599-7295

Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

UNC Lineberger Comprehensive Cancer Center

OTHER

NCT00719173 - Effect of Aprepitant on Cyclophosphamide Pharmacokinetics in Patients With Breast Cancer | Biotech Hunter | Biotech Hunter