105
Participants
Start Date
April 30, 2006
Primary Completion Date
March 31, 2010
Study Completion Date
March 31, 2010
buprenorphine taper followed by naltrexone maintenance
direct comparison of 1-, 2- and 4-week durations of buprenorphine taper for treating prescription opioid abusers; those who successfully taper without resumption of illicit opioid use are subsequently transitioned to oral naltrexone therapy for the remainder of the 12-week trial; all participants receive a platform of intensive individual behavioral therapy and on-site urinalysis monitoring throughout the trial
Behavioral therapy
Substance Abuse Treatment Center, University of Vermont, Burlington
National Institute on Drug Abuse (NIDA)
NIH
University of Vermont Medical Center
OTHER