Effects of Tranilast on Pharmacokinetics of Methotrexate (MTX) in Patients With Rheumatoid Arthritis (RA)

PHASE1WithdrawnINTERVENTIONAL
0
Timeline

Start Date

September 30, 2008

Primary Completion Date

September 30, 2009

Study Completion Date

September 30, 2009

Conditions
Rheumatoid Arthritis
Interventions
DRUG

Tranilast

Tranilast (300mg twice a day) for a period of seven days whilst taking their weekly prescribed dose of methotrexate. Followed by a 7 day washout period before starting arm 2

DRUG

Placebo comparator

The patient will receive the placebo capsule twice a day whilst receiving their weekly dose of methotrexate

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Nuon Therapeutics, Inc.

INDUSTRY

lead

Imperial College London

OTHER