NCT00697892View on ClinicalTrials.gov

Pharmacokinetic Interactions Between Antiretroviral Agents and Antimalarial Drug Combinations

PHASE1CompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

July 31, 2005

Primary Completion Date

December 31, 2008

Study Completion Date

December 31, 2010

Conditions
HIV InfectionsMalaria
Interventions
DRUG

lopinavir/ritonavir

Two tablets of lopinavir 200mg / ritonavir 50mg orally twice daily with food for 26 days

DRUG

efavirenz

One 600mg tablet orally once daily before bedtime on an empty stomach for 26 days

DRUG

artemether/lumefantrine

4 tablets of artemether 20mg/lumefantrine 120mg twice daily with food. 2 three-day courses will be administered (with washout in between) during the duration of the trial.

Trial Locations (1)

94110

San Francisco General Hospital, San Francisco

All Listed Sponsors
lead

Fran Aweeka

OTHER

NCT00697892 - Pharmacokinetic Interactions Between Antiretroviral Agents and Antimalarial Drug Combinations | Biotech Hunter | Biotech Hunter