Effect of Homocysteine-lowering Therapy With Folic Acid, Vitamin B12, and Vitamin B6 on Endothelium-dependent Vasodilatation of Forearm Resistance Vessels in Patients With Coronary Heart Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

January 31, 2005

Primary Completion Date

February 28, 2007

Study Completion Date

April 30, 2007

Conditions
Cardiovascular DiseaseEndothelial Dysfunction
Interventions
DRUG

folic acid, vitamin B12 and B6 and rosuvastatin

Vitamin supplementation with folic acid 1mg/d, vitamin B12 0.4mg/d and B6 10mg/d po for 6 weeks alone vs. rosuvastatin 10mg/d for 6 weeks alone and thereafter combined treatment for 6 weeks

All Listed Sponsors
lead

Insel Gruppe AG, University Hospital Bern

OTHER

NCT00693589 - Effect of Homocysteine-lowering Therapy With Folic Acid, Vitamin B12, and Vitamin B6 on Endothelium-dependent Vasodilatation of Forearm Resistance Vessels in Patients With Coronary Heart Disease | Biotech Hunter | Biotech Hunter