Zyban as an Effective Smoking Cessation Aid for Patients Following an Acute Coronary Syndrome: The ZESCA Trial

PHASE3CompletedINTERVENTIONAL
Enrollment

392

Participants

Timeline

Start Date

December 31, 2005

Primary Completion Date

June 30, 2010

Study Completion Date

June 30, 2010

Conditions
Acute Coronary SyndromeMyocardial InfarctionSmoking
Interventions
DRUG

Bupropion HCl ER

150 mg tablets po qd for 3 days and then 150 mg po bid for remainder of 9 weeks

DRUG

Placebo

Placebo

Trial Locations (38)

13326

Bassett Healthcare, Cooperstown

13790

United Health Services, Johnson City

18501

Advanced Cardiology Specialists, Scranton

23601

Riverside Hospital, Newport News

25309

Charleston Area Medical Center, South Charleston

29403

Medical University of South Carolina, Charleston

45429

Schuster Cardiology, Kettering

Southwest Cardiology, Kettering

73104

DVA Medical Center, Oklahoma City

81003

Parkview Medcial Center, Pueblo

04240

Central Maine Medical Center, Lewiston

Unknown

Bay Regional Medical Center, Bay City

National Heart Foundation of Bangladesh, Dhaka

Peter Lougheed Centre of the Calgary General Hospital, Calgary

University of Alberta Hospital, Edmonton

St. Boniface General Hospital, Winnipeg

New Brunswick Heart Centre, Saint Johns

Valley Regional Hospital, Kentville

The Ottawa Hospital, General Campus, Ottawa

St. Michael's Hospital, Toronto

CHA Hotel-Dieu de Levis, Lévis

Hopital Sacre-Coeur de Montreal, Montreal

Hotel-Dieu, Montreal

Montreal General Hospital, Montreal

CSSS de Sorel-Tracy, Sorel-Tracy

CSSS de la Region de Thetford, Thetford-Mines

Centre for Chronic Disease Control, New Delhi

Isfahan Cardiovascular Research Centre, Isfahan

InterActive Research and Development, Karachi

University Hospital F. Bourguiba, Sousse

11794-8167

Stony Brook Hospital and Medical Center, Stony Brook

V5M 1L9

Vancouver Coastal Health, Vancouver

R3T 2E8

Victoria General Hospital, Winnipeg

H7M 3L9

Hopital de la Cite de la Sante, Laval

H3T 1E2

SMBD- Jewish General Hospital, Montreal

G1V 4G5

Hopital Laval, Québec

J1H 5N4

Hopital Fleurimont, Sherbrooke

S7N 0W8

Saskatchewan Drug Research Institute, Saskatoon

All Listed Sponsors
collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

collaborator

Heart and Stroke Foundation of Canada

OTHER

lead

Mark Eisenberg

OTHER

NCT00689611 - Zyban as an Effective Smoking Cessation Aid for Patients Following an Acute Coronary Syndrome: The ZESCA Trial | Biotech Hunter | Biotech Hunter