A Study to Investigate the Pharmacology of a Dual Pharmacophore in Healthy Volunteers

PHASE1CompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

March 10, 2008

Primary Completion Date

May 27, 2008

Study Completion Date

May 27, 2008

Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
DRUG

GSK961081

GSK961081 multidose dry powder inhaler (Diskus inhaler) will be available with dosing strengths of 400 micrograms and 1200 micrograms administered once daily in the morning.

DRUG

GSK961081 matching placebo

GSK961081 matching placebo multidose dry powder inhaler (Diskus inhaler) will be available to be administered once daily in the morning.

DRUG

Propranolol

Propranolol over encapsulated tablet will be available with dosing strengths of 40 milligrams administered orally with 240 milliliters of water.

DRUG

Propranolol matching placebo

Propranolol matching placebo over encapsulated tablet will be available to be administered orally with 240 milliliters of water.

Trial Locations (1)

HA1 3UJ

GSK Investigational Site, Harrow

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

GlaxoSmithKline

INDUSTRY

lead

Theravance Biopharma

INDUSTRY

NCT00687700 - A Study to Investigate the Pharmacology of a Dual Pharmacophore in Healthy Volunteers | Biotech Hunter | Biotech Hunter