Cardiac Surgery: In Vivo Titration of Protamine

NACompletedINTERVENTIONAL
Enrollment

138

Participants

Timeline

Start Date

June 30, 2008

Primary Completion Date

June 30, 2011

Study Completion Date

June 30, 2011

Conditions
Bleeding
Interventions
PROCEDURE

Titration protamine

10\. Study group: celite ACT will be performed every 3 minutes during protamine infusion until ACT values suggest reach of a plateau (defined as 2 similar ACT values, within 10% variability, and ACT ≤ to 160 seconds.), time at which infusion will be stopped. 2cc of blood is required per ACT test, for a maximum total of 10cc.

DRUG

Standard administration of protamine

1.3 mg of Protamine for 100u héparine

Trial Locations (1)

H1T 1C8

Montreal Heart Institute, Montreal

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Organon

INDUSTRY

lead

Montreal Heart Institute

OTHER

NCT00684450 - Cardiac Surgery: In Vivo Titration of Protamine | Biotech Hunter | Biotech Hunter