Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients

PHASE3UnknownINTERVENTIONAL
Enrollment

291

Participants

Timeline

Start Date

July 31, 2008

Primary Completion Date

July 31, 2013

Study Completion Date

July 31, 2013

Conditions
Marfan Syndrome
Interventions
DRUG

Losartan and nebivolol

"Nebivolol is administered orally as pills. It is given preferentially once a day in the morning or, if not well tolerated because of hypotension, the total daily dosage is given in two administrations.~Losartan is administered orally as pills. It is given preferentially once a day or, if not well tolerated because of hypotension, the total daily dosage is given in two administrations"

DRUG

Losartan

Losartan is administered orally as pills. It is given preferentially once a day or, if not well tolerated because of hypotension, the total daily dosage is given in two administrations

DRUG

Nebivolol

Nebivolol is administered orally as pills. It is given preferentially once a day in the morning or, if not well tolerated because of hypotension, the total daily dosage is given in two administrations

Trial Locations (1)

27100

RECRUITING

IRCCS Foundation San Matteo Hospital, Pavia

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

collaborator

Menarini Group

INDUSTRY

lead

Fondazione IRCCS Policlinico San Matteo di Pavia

OTHER

NCT00683124 - Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients | Biotech Hunter | Biotech Hunter