A Comparative Study of Artekin With Standard Malarial Treatment Regimes in Afghanistan

PHASE3CompletedINTERVENTIONAL
Enrollment

1,086

Participants

Timeline

Start Date

July 31, 2007

Primary Completion Date

February 28, 2010

Study Completion Date

February 28, 2010

Conditions
Uncomplicated Falciparum MalariaVivax Malaria
Interventions
DRUG

Dihydroartemisinin + Piperaquine (Artekin)

An adult dose consists of four doses of two tablets, given at 0, 8, 24 and 48 h. The approximate total adult dose is 6/48 mg/kg (DHA/PPQ). For children, a dose of 1.6/12.8 mg/kg is given at the same time intervals; this dosage will be obtained by dissolving the tablets in 5 ml of water.

DRUG

artesunate-sulphadoxin/pyrimethamine, chloroquine

The standard treatment will be in accordance with that in Afghanistan

Trial Locations (4)

Unknown

Provincial Malaria Control Centers (MRC), Faryab

Provincial Malaria Control Centers (MRC), Jalalabad

Provincial Malaria Control Centers (MRC), Maymana

Provincial Malaria Control Centers (MRC), Takhar

All Listed Sponsors
collaborator

Wellcome Trust

OTHER

collaborator

Ministry of public Health Afghanistan

UNKNOWN

lead

University of Oxford

OTHER

NCT00682578 - A Comparative Study of Artekin With Standard Malarial Treatment Regimes in Afghanistan | Biotech Hunter | Biotech Hunter