Blood Pressure and Weight Trajectory on a Dual Antihypertensive Combination Plus Sibutramine Versus Placebo in Obese Hypertensives

PHASE3CompletedINTERVENTIONAL
Enrollment

171

Participants

Timeline

Start Date

February 28, 2002

Primary Completion Date

December 31, 2003

Conditions
ObesityHypertension
Interventions
DRUG

sibutramine

8-wks, sibutramine, 10 mg, capsules, once daily

DRUG

sibutramine

8-wks, sibutramine, 15 mg, capsules, once daily

DRUG

verapamil/trandolapril

2 wk Run-in phase, antihypertensive therapy only

DRUG

metoprolol/HCT

2 wk Run-in phase, antihypertensive therapy only

DRUG

felodipine/ramipril

2 wk Run-in phase, antihypertensive therapy only

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Abbott

INDUSTRY