A Randomized Clinical Trial To Study Losartan On Endothelial Dysfunction and Insulin Resistance In Obese Patients

PHASE4CompletedINTERVENTIONAL
Enrollment

53

Participants

Timeline

Start Date

May 31, 2007

Primary Completion Date

December 31, 2008

Study Completion Date

December 31, 2008

Conditions
ObesityHypertensionHyperglycemia
Interventions
DRUG

losartan

losartan 100 mg tablets 1 tab po QD

DRUG

Placebo control

Placebo 1 po QD

Trial Locations (9)

10025

St. Lukes Roosevelt Hospital, New York

19104

University of Pennsylvania School of Medicine, Philadelphia

33136

University of Miami Diabetes Research Institute, Miami

46202

Indiana University School of Medicine, Indianapolis

72205

CAVS Clinical Research Center, Little Rock

75390

University of Texas SW Medical Center at Dallas, Dallas

77030

Hypertension Clinical Pharmacology Baylor Clinic, Houston

92161

VA San Diego Health Care System, San Diego

02115

Brigham and Women's Hospital Cardiovascular Division, Boston

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Brigham and Women's Hospital

OTHER

NCT00675987 - A Randomized Clinical Trial To Study Losartan On Endothelial Dysfunction and Insulin Resistance In Obese Patients | Biotech Hunter | Biotech Hunter