Effectiveness of Alcohol Interventions Among Tuberculosis (TB) Patients in Tomsk Oblast, Russia

NACompletedINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

January 31, 2007

Primary Completion Date

June 30, 2011

Study Completion Date

June 30, 2011

Conditions
TuberculosisAlcohol Use Disorders
Interventions
BEHAVIORAL

Brief Counseling Intervention (BCI)

Two-tiered BCI characterized by both primary and secondary interventions. Primary BCI treatment format consists of 6 discussions delivered monthly in the first 6 months of standard TB treatment. 10-15 minutes long. Secondary BCI is delivered on a monthly basis while receiving TB treatment. 5-10 minutes long.

DRUG

Naltrexone

Opioid antagonist, which decreases the pleasurable response to and craving for alcohol consumption. Oral; single daily dose of 50 mg per day for 6 months.

OTHER

BCI + Naltrexone

Combination of the two previous interventions

BEHAVIORAL

Treatment as Usual

Services provided by psychologists and narcologists (additions specialists) employed by the Tomsk Oblast TB Services.

Trial Locations (1)

Unknown

Tomsk Oblast TB Services, Tomsk

All Listed Sponsors
collaborator

Mclean Hospital

OTHER

collaborator

Harvard School of Public Health (HSPH)

OTHER

lead

Brigham and Women's Hospital

OTHER

NCT00675961 - Effectiveness of Alcohol Interventions Among Tuberculosis (TB) Patients in Tomsk Oblast, Russia | Biotech Hunter | Biotech Hunter