The Blood Pressure and Metabolic Effects of Nebivolol in Hypertensive Patients With Impaired Glucose Tolerance or Impaired Fasting Glucose

PHASE4CompletedINTERVENTIONAL
Enrollment

537

Participants

Timeline

Start Date

May 15, 2008

Primary Completion Date

July 9, 2010

Study Completion Date

July 9, 2010

Conditions
Hypertension
Interventions
DRUG

Nebivolol with concomitant losartan or lisinopril

Encapsulated Nebivolol 5 mg, 10 mg, 20, mg, 40 mg total daily dosage, oral administration with concomitant treatment consisting of lisinopril 10 mg total daily dosage, oral administration or losartan 50 mg total daily dosage, oral administration.

DRUG

HCTZ with concomitant losartan or lisinopril

Encapsulated Hydrochlorothiazide 12.5 mg or 25 mg total daily dosage, oral administration with concomitant treatment consisting of lisinopril 10 mg total daily dosage, oral administration or losartan 50 mg total daily dosage, oral administration.

DRUG

Placebo with concomitant losartan or lisinopril

Placebo with concomitant treatment consisting of lisinopril 10 mg total daily dosage, oral administration or losartan 50 mg total daily dosage, oral administration.

Trial Locations (88)

10001

Forest Investigative Site 081, New York

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Forest Investigative Site 071, Brooklyn

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Forest Investigative Site 114, Harleysville

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Forest Investigative Site 006, Oxon Hill

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Forest Investigative Site 126, Arlington

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Forest Investigative Site 077, Durham

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Forest Investigative Site 050, Salisbury

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Forest Investigative Site 035, Charlotte

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Forest Investigative Site 051, Charlotte

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Forest Investigative Site 041, Morehead City

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Forest Investigative Site 100, Lenoir

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Forest Investigative Site 098, Columbia

Forest Investigative Site 105, Simpsonville

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Forest Investigative Site 115, Greer

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Forest Investigative Site 075, Atlanta

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Forest Investigative Site 072, Atlanta

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Forest Investigative Site 042, Augusta

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Forest Investigative Site 019, Daytona Beach

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Forest Investigative Site 010, DeLand

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Forest Investigative Site 073, Hialeah

Forest Investigative Site 109, Hialeah

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Forest Investigative Site 036, Hollywood

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Forest Investigative Site 107, Pembroke Pines

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Forest Investigative Site 103, Coral Gables

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Forest Investigative Site 104, Miami

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Forest Investigative Site 121, Miami

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Forest Investigative Site 099, Miami

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Forest Investigative Site 060, West Palm Beach

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Forest Investigative Site 125, West Palm Beach

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Forest Investigative Site 140, Tampa

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Forest Investigative Site 141, St. Petersburg

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Forest Investigative Site 139, Brooksville

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Forest Investigative Site 101, Birmingham

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Forest Investigative Site 058, Athens

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Forest Investigative Site 016, Huntsville

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Forest Investigative Site 065, Madisonville

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Forest Investigative Site 122, Perrysburg

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Forest Investigative Site 089, Cincinnati

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Forest Investigative Site 091, Centerville

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Forest Investigative Site 021, Saint Clair Shores

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Forest Investigative Site 018, Paw Paw

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Forest Investigative Site 092, Sioux Falls

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Forest Investigative Site 082, Chicago

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Forest Investigative Site 080, Columbia

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Forest Investigative Site 096, Wichita

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Forest Investigative Site 123, Lafayette

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Forest Investigative Site 116, Houston

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Forest Investigative Site 048, Sugar Land

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Forest Investigative Site 012, San Antonio

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Forest Investigative Site 120, Odessa

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Forest Investigative Site 95, Meridian

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Forest Investigative Site 130, West Jordan

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Forest Investigative Site 062, Salt Lake City

Forest Investigative Site 093, Salt Lake City

85020

Forest Investigative Site 119, Phoenix

85715

Forest Investigative Site 078, Tucson

90057

Forest Investigative Site 085, Los Angeles

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Forest Investigative Site 097, Bell Gardens

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Forest Investigative Site 028, Los Angeles

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Forest Investigative Site 127, Huntington Park

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Forest Investigative Site 026, Buena Park

Forest Investigative Site 147, Buena Park

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Forest Investigative Site 030, Long Beach

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Forest Investigative Site 061, Chino

91950

Forest Investigative Site 124, National City

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Forest Investigative Site 054, Encinitas

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Forest Investigative Site 068, San Diego

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Forest Investigative Site 117, Riverside

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Forest Investigative Site 063, Temecula

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Forest Investigative Site 108, Costa Mesa

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Forest Investigative Site 112, Santa Ana

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Forest Investigative Site 013, Tustin

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Forest Investigative Site 056, Anaheim

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Forest Investigative Site 128, Fresno

94598

Forest Investigative Site 052, Walnut Creek

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Forest Investigative Site 025, Roseville

95821

Forest Investigative Site 017, Sacramento

96814

Forest Investigative Site 094, Honolulu

97210

Forest Investigative Site 088, Portland

97404

Forest Investigative Site 087, Eugene

06460

Forest Investigative Site 074, Milford

04210

Forest Investigative Site 106, Auburn

02301

Forest Investigative Site 067, Brockton

Forest Investigative Site 110, Brockton

07202

Forest Investigative Site 146, Elizabeth

02860

Forest Investigative Site 083, Pawtucket

75006-5810

Forest Investigative Site 003, Carrollton

84010-5174

Forest Investigative Site 040, Bountiful

Sponsors
All Listed Sponsors
lead

Forest Laboratories

INDUSTRY