NCT00673621View on ClinicalTrials.gov

A Study Designed to Determine if the Pharmacokinetic Disposition of Inhaled Insulin Exposure is the Same for Asthmatics and Non-asthmatics

PHASE1CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

May 31, 2008

Primary Completion Date

November 30, 2008

Study Completion Date

December 31, 2008

Conditions
AsthmaDiabetes Mellitus
Interventions
DRUG

Technosphere Insulin Inhalation Powder

3.0 of human insulin. single dose cartridges filled with 5 or 10 mg of Technosphere Inhalation Powder, containing 15 or 30 u of insulin

DRUG

Salbutamol (Albuterol)

2 puff = 200 mcg total dose

DRUG

Methacholine chloride

5mls of methacholine; diluent sodium chloride 0.9%; formulation methacholine chloride in sodium chloride 0.9%

Trial Locations (2)

M23 9QZ

Medicines Evaluation Unit (MEU), Manchester

M15 6SH

ICON Development Solutions, Manchester

Sponsors
All Listed Sponsors
lead

Mannkind Corporation

INDUSTRY