Trial Of CP-751, 871 And Erlotinib In Refractory Lung Cancer

PHASE3TerminatedINTERVENTIONAL
Enrollment

583

Participants

Timeline

Start Date

May 31, 2008

Primary Completion Date

March 31, 2011

Study Completion Date

April 30, 2012

Conditions
Carcinoma, Large CellCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellCarcinoma, Adenosquamous Cell
Interventions
DRUG

CP 751,871 (Figitumumab)

CP 751,871 (20 mg/kg) will be administered as an IV infusion on study Days 1 and 2 in Cycle 1, and every three weeks (from Day 1) (Cycle) thereafter.

DRUG

Erlotinib

Erlotinib (one tablet of 150 mg/day PO).

DRUG

Erlotinib

Erlotinib (one tablet of 150 mg/day PO). Erlotinib will be taken at least one hour before or two hours after the ingestion of food.

Trial Locations (175)

8

Pfizer Investigational Site, Dublin

112

Pfizer Investigational Site, Taipei

333

Pfizer Investigational Site, Taoyuan

404

Pfizer Investigational Site, Taichung

1000

Pfizer Investigational Site, Ljubljana

1233

Pfizer Investigational Site, Sofia

1525

Pfizer Investigational Site, Budapest

1527

Pfizer Investigational Site, Sofia

1756

Pfizer Investigational Site, Sofia

2930

Pfizer Investigational Site, Brasschaat

7000

Pfizer Investigational Site, Mons

Pfizer Investigational Site, Chur

7925

Pfizer Investigational Site, Cape Town

8000

Pfizer Investigational Site, Székesfehérvár

9000

Pfizer Investigational Site, Varna

9301

Pfizer Investigational Site, Bloemfontein

10043

Pfizer Investigational Site, Orbassano (TO)

10461

Pfizer Investigational Site, The Bronx

10467

Pfizer Investigational Site, The Bronx

11000

Pfizer Investigational Site, Belgrade

11030

Pfizer Investigational Site, Manhasset

11040

Pfizer Investigational Site, New Hyde Park

11042

Pfizer Investigational Site, Lake Success

13009

Pfizer Investigational Site, Marseille

13230

Pfizer Investigational Site, Jakarta

13915

Pfizer Investigational Site, Marseille

14221

Pfizer Investigational Site, Amherst

14263

Pfizer Investigational Site, Buffalo

17007

Pfizer Investigational Site, Girona

19104

Pfizer Investigational Site, Philadelphia

19107

Pfizer Investigational Site, Philadelphia

20817

Pfizer Investigational Site, Bethesda

21204

Pfizer Investigational Site, Kamenitz

23061

Pfizer Investigational Site, Glouster

23185

Pfizer Investigational Site, Williamsburg

23601

Pfizer Investigational Site, Gloucester

Pfizer Investigational Site, Newport News

26204

Pfizer Investigational Site, Nová Ves pod Pleší

28007

Pfizer Investigational Site, Madrid

28033

Pfizer Investigational Site, Madrid

28041

Pfizer Investigational Site, Madrid

29609

Pfizer Investigational Site, Brest

30005

Pfizer Investigational Site, Alpharetta

30033

Pfizer Investigational Site, Decatur

30041

Pfizer Investigational Site, Cumming

30046

Pfizer Investigational Site, Lawrenceville

30078

Pfizer Investigational Site, Snellville

30094

Pfizer Investigational Site, Conyers

30096

Pfizer Investigational Site, Duluth

30236

Pfizer Investigational Site, Lake Spivey

30308

Pfizer Investigational Site, Atlanta

30322

Pfizer Investigational Site, Atlanta

30342

Pfizer Investigational Site, Atlanta

32024

Pfizer Investigational Site, Lake City

32055

Pfizer Investigational Site, Lake City

33006

Pfizer Investigational Site, Oviedo

33021

Pfizer Investigational Site, Hollywood

33028

Pfizer Investigational Site, Pembroke Pines

33081

Pfizer Investigational Site, Aviano (PN)

35033

Pfizer Investigational Site, Rennes

35128

Pfizer Investigational Site, Padua

38138

Pfizer Investigational Site, Germantown

38652

Pfizer Investigational Site, New Albany

38700

Pfizer Investigational Site, La Tronche

40005

Pfizer Investigational Site, Sumy

40207

Pfizer Investigational Site, Louisville

41009

Pfizer Investigational Site, Seville

41013

Pfizer Investigational Site, Seville

41100

Pfizer Investigational Site, Modena

41110

Pfizer Investigational Site, Larissa

42277

Pfizer Investigational Site, Saint-Priest-en-Jarez

43210

Pfizer Investigational Site, Columbus

43221

Pfizer Investigational Site, Columbus

46107

Pfizer Investigational Site, Beech Grove

46237

Pfizer Investigational Site, Indianapolis

46260

Pfizer Investigational Site, Indianapolis

47841

Pfizer Investigational Site, Cattolica (RN)

47900

Pfizer Investigational Site, Rimini

49102

Pfizer Investigational Site, Dnipropetrovsk

50701

Pfizer Investigational Site, Waterloo

52402

Pfizer Investigational Site, Cedar Rapids

59102

Pfizer Investigational Site, Billings

59701

Pfizer Investigational Site, Butte

60286

Pfizer Investigational Site, Surabaya

61070

Pfizer Investigational Site, Kharkiv

61615

Pfizer Investigational Site, Peoria

61701

Pfizer Investigational Site, Bloomington

71110

Pfizer Investigational Site, Heraklion

71913

Pfizer Investigational Site, Hot Springs

72903

Pfizer Investigational Site, Fort Smith

73071

Pfizer Investigational Site, Norman

73102

Pfizer Investigational Site, Oklahoma City

73109

Pfizer Investigational Site, Oklahoma City

73120

Pfizer Investigational Site, Oklahoma City

74104

Pfizer Investigational Site, Tulsa

74133

Pfizer Investigational Site, Tulsa

74136

Pfizer Investigational Site, Tulsa

78229

Pfizer Investigational Site, San Antonio

80026

Pfizer Investigational Site, Lafayette

80205

Pfizer Investigational Site, Denver

82414

Pfizer Investigational Site, Cody

83092

Pfizer Investigational Site, Donetsk

83100

Pfizer Investigational Site, Avellino

91360

Pfizer Investigational Site, Thousand Oaks

Pfizer Investigational Site, Westlake Valley

92868

Pfizer Investigational Site, Orange

94805

Pfizer Investigational Site, Villejuif

94954

Pfizer Investigational Site, Petaluma

95403

Pfizer Investigational Site, Santa Rosa

95453

Pfizer Investigational Site, Lakeport

97448

Pfizer Investigational Site, Saint Pierre La Réunion Cedex

98801

Pfizer Investigational Site, Wenatchee

115478

Pfizer Investigational Site, Moscow

143423

Pfizer Investigational Site, Moscow

194044

Pfizer Investigational Site, Saint Petersburg

198255

Pfizer Investigational Site, Saint Petersburg

350040

Pfizer Investigational Site, Krasnodar

354057

Pfizer Investigational Site, Sochi

400015

Pfizer Investigational Site, Cluj-Napoca

Pfizer Investigational Site, Cluj-Napoca

700106

Pfizer Investigational Site, Iași

8380455

Pfizer Investigational Site, Independencia

92868-3298

Pfizer Investigational Site, Orange

03756

Pfizer Investigational Site, Lebanon

03102

Pfizer Investigational Site, Manchester

22908-0334

Pfizer Investigational Site, Charlottesville

22908-0716

Pfizer Investigational Site, Charlottesville

26003-6300

Pfizer Investigational Site, Wheeling

20230 -130

Pfizer Investigational Site, Rio de Janeiro

20231 -050

Pfizer Investigational Site, Rio de Janeiro

90035-903

Pfizer Investigational Site, Porto Alegre

01224-010

Pfizer Investigational Site, Higienópolis

Pfizer Investigational Site, São Paulo

09060-650

Pfizer Investigational Site, Santo André

01219-000

Pfizer Investigational Site, São Paulo

01221-020

Pfizer Investigational Site, São Paulo

M5G 2M9

Pfizer Investigational Site, Toronto

H3T 1E2

Pfizer Investigational Site, Montreal

284 01

Pfizer Investigational Site, Kutná Hora

180 81

Pfizer Investigational Site, Prague

390 03

Pfizer Investigational Site, Tábor

59020 Cedex

Pfizer Investigational Site, Lille

H-3233

Pfizer Investigational Site, Mátraháza

Unknown

Pfizer Investigational Site, Cork

Pfizer Investigational Site, Dublin

Pfizer Investigational Site, Ch-4101 Bruderholz

00157

Pfizer Investigational Site, Roma

LV 1002

Pfizer Investigational Site, Riga

LV 1079

Pfizer Investigational Site, Riga

85-796

Pfizer Investigational Site, Bydgoszcz

80-952

Pfizer Investigational Site, Gdansk

31-108

Pfizer Investigational Site, Krakow

31-215

Pfizer Investigational Site, Krakow

20-954

Pfizer Investigational Site, Lublin

10-357

Pfizer Investigational Site, Olsztyn

10-513

Pfizer Investigational Site, Olsztyn

44-200

Pfizer Investigational Site, Rybnik

44-300

Pfizer Investigational Site, Wodzislaw Sl.

00716

Pfizer Investigational Site, Ponce

410-769

Pfizer Investigational Site, Gyeonggi-do

120-752

Pfizer Investigational Site, Seoul

138-736

Pfizer Investigational Site, Seoul

03203

Pfizer Investigational Site, Elche

08025

Pfizer Investigational Site, Barcelona

08097

Pfizer Investigational Site, L'Hospitalet de Llobregat

08243

Pfizer Investigational Site, Manresa

08208

Pfizer Investigational Site, Sabadell

CH-4031

Pfizer Investigational Site, Basel

CH-4058

Pfizer Investigational Site, Basel

CH-4410

Pfizer Investigational Site, Liestal

03115

Pfizer Investigational Site, Kyiv

SM2 5PT

Pfizer Investigational Site, Sutton

SW3 6JJ

Pfizer Investigational Site, London

W6 8RF

Pfizer Investigational Site, London

M20 4BX

Pfizer Investigational Site, Manchester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY