Lesion Dosimetry With 124-Iodine in Metastatic Thyroid Carcinoma

PHASE1CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 7, 2005

Primary Completion Date

October 2, 2025

Study Completion Date

October 2, 2025

Conditions
Thyroid Cancer
Interventions
RADIATION

131 I-iodine (131-I), 124 I-iodine (124-I)

Those who have demonstrated metastases which concentrate radioiodine will undergo routine testing to determine the MTA for blood and lung tissue. This will be performed with 124-I instead of 131-I. If the diagnostic scans (done with 123-I) show that the metastatic lesions concentrate radioiodine, the patient will be treated with 131-I based on standard of care discussions at a tumor board meeting. One week following the 131-I therapy, a whole body scan will be obtained and compared with the 124-I diagnostic scan. One year later, another extent of disease workup will be performed which will include 124-I dosimetry and scanning.

Trial Locations (1)

10065

Memorial Sloan Kettering Cancer Center, New York

All Listed Sponsors
collaborator

Gustave Roussy, Cancer Campus, Grand Paris

OTHER

lead

Memorial Sloan Kettering Cancer Center

OTHER

NCT00673010 - Lesion Dosimetry With 124-Iodine in Metastatic Thyroid Carcinoma | Biotech Hunter | Biotech Hunter