Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivity

PHASE2CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

October 31, 2007

Primary Completion Date

December 31, 2008

Study Completion Date

September 30, 2009

Conditions
Celiac Disease
Interventions
BIOLOGICAL

Necator americanus

10 necator americanus larvae will be inoculated at week 0 with a further 5 larvae inoculated at week 12

OTHER

Sham inoculation

A diluted amount of McIlhenny \& Co Tabasco Pepper Sauce will be applied via a gauze dressing at weeks 0 and 12.

Trial Locations (3)

4006

Queensland Institute of Medical Research, Brisbane

4102

Princess Alexandra Hospital, Brisbane

4131

Logan Hospital, Logan City

All Listed Sponsors
collaborator

The Broad Foundation

OTHER

collaborator

Townsville Hospital

OTHER_GOV

collaborator

James Cook University, Queensland, Australia

OTHER

collaborator

Walter and Eliza Hall Institute of Medical Research

OTHER

collaborator

Queensland Institute of Medical Research

OTHER

lead

Princess Alexandra Hospital, Brisbane, Australia

OTHER

NCT00671138 - Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivity | Biotech Hunter | Biotech Hunter