652
Participants
Start Date
October 7, 2008
Primary Completion Date
August 1, 2012
Study Completion Date
July 27, 2022
trastuzumab
IV q weekly (loading dose 4mg/kg; subsequent doses 2mg/kg) or IV q 3 weekly (loading dose 8mg/kg, subsequent doses 6mg/kg).
docetaxel
75mg/m2 IV q 3 weekly, day 1 of a 3 week cycle for 8 cycles plus G-CSF (when given together with lapatinib).
lapatinib ditosylate
1250 mg once daily (while given with taxane). 1500mg once daily (when given alone after taxane completion).
paclitaxel
80mg/m2 IV q weekly days 1, 8 and 15 of a 4-week cycle for 6 cycles.
Novartis Investigative Site, Taipei
Novartis Investigative Site, Taipei
Novartis Investigative Site, Taichung
Novartis Investigative Site, Changhua
Novartis Investigative Site, Tainan County
Novartis Investigative Site, Jette
Novartis Investigative Site, North Sydney
Novartis Investigative Site, Liverpool
Novartis Investigative Site, Tweed Heads
Novartis Investigative Site, Garran
Novartis Investigative Site, Santa Fe
Novartis Investigative Site, Fitzroy
Novartis Investigative Site, Box Hill
Novartis Investigative Site, Wodonga
Novartis Investigative Site, San Miguel de Tucumán
Novartis Investigative Site, Liège
Novartis Investigative Site, Woolloongabba
Novartis Investigative Site, Adelaide
Novartis Investigative Site, Namur
Novartis Investigative Site, Kurralta Park
Novartis Investigative Site, Bedford Park
Novartis Investigative Site, Subiaco
Novartis Investigative Site, Hobart
Novartis Investigative Site, Ghent
Novartis Investigative Site, Berlin
Novartis Investigative Site, Berlin
Novartis Investigative Site, Gyeonggi-do
Novartis Investigative Site, Bangkok
Novartis Investigative Site, Marseille
Novartis Investigative Site, Cooperstown
Novartis Investigative Site, Caen
Novartis Investigative Site, Brandenburg
Novartis Investigative Site, A Coruña
Novartis Investigative Site, Poria – Neve Oved
Novartis Investigative Site, Fürstenwalde
Novartis Investigative Site, Genoa
Novartis Investigative Site, Girona
Novartis Investigative Site, Hamburg
Novartis Investigative Site, Wheaton
Novartis Investigative Site, Towson
Novartis Investigative Site, Hamburg
Novartis Investigative Site, Hamburg
Novartis Investigative Site, Jaén
Novartis Investigative Site, Chesapeake
Novartis Investigative Site, Lübeck
Novartis Investigative Site, Salem
Novartis Investigative Site, Leer
Novartis Investigative Site, Lugo
Novartis Investigative Site, Greensboro
Novartis Investigative Site, Madrid
Novartis Investigative Site, Madrid
Novartis Investigative Site, Madrid
Novartis Investigative Site, Majadahonda (Madrid)
Novartis Investigative Site, Pozuelo de Alarcon (Madrid)
Novartis Investigative Site, Alcorcón
Novartis Investigative Site, Columbia
Novartis Investigative Site, Lawrenceville
Novartis Investigative Site, Hanover
Novartis Investigative Site, Augusta
Novartis Investigative Site, Savannah
Novartis Investigative Site, Porta Westfalica
Novartis Investigative Site, Bordeaux
Novartis Investigative Site, Bordeaux
Novartis Investigative Site, Aviano (PN)
Novartis Investigative Site, Loxahatchee Groves
Novartis Investigative Site, Bielefeld
Novartis Investigative Site, New Port Richey
Novartis Investigative Site, Kissimmee
Novartis Investigative Site, Lich
Novartis Investigative Site, Fulda
Novartis Investigative Site, Memphis
Novartis Investigative Site, Goslar
Novartis Investigative Site, Sumy
Novartis Investigative Site, Seville
Novartis Investigative Site, Velbert
Novartis Investigative Site, Nantes
Novartis Investigative Site, Wooster
Novartis Investigative Site, Canton
Novartis Investigative Site, Essen
Novartis Investigative Site, Valencia
Novartis Investigative Site, Indianapolis
Novartis Investigative Site, Munster
Novartis Investigative Site, Goshen
Novartis Investigative Site, New Albany
Novartis Investigative Site, Evansville
Novartis Investigative Site, Coesfeld
Novartis Investigative Site, Angers
Novartis Investigative Site, Petah Tikva
Novartis Investigative Site, Dnipropetrovsk
Novartis Investigative Site, Dnipro
Novartis Investigative Site, Chiang Mai
Novartis Investigative Site, Cologne
Novartis Investigative Site, Ramat Gan
Novartis Investigative Site, Bonn
Novartis Investigative Site, Milwaukee
Novartis Investigative Site, Troisdorf
Novartis Investigative Site, Koblenz
Novartis Investigative Site, Holon
Novartis Investigative Site, Witten
Novartis Investigative Site, Prato (PO)
Novartis Investigative Site, Bozeman
Novartis Investigative Site, Oak Lawn
Novartis Investigative Site, Frankfurt am Main
Novartis Investigative Site, Chicago
Novartis Investigative Site, Cuernavaca
Novartis Investigative Site, Chieti
Novartis Investigative Site, Saarbrücken
Novartis Investigative Site, Strasbourg
Novartis Investigative Site, Grand Island
Novartis Investigative Site, Kearney
Novartis Investigative Site, Kearney
Novartis Investigative Site, Heidelberg
Novartis Investigative Site, Stuttgart
Novartis Investigative Site, Hot Springs
Novartis Investigative Site, Lecce
Novartis Investigative Site, Metz-Tessy
Novartis Investigative Site, Paris
Novartis Investigative Site, Lviv
Novartis Investigative Site, Denver
Novartis Investigative Site, Colorado Springs
Novartis Investigative Site, Rosenheim
Novartis Investigative Site, Post Falls
Novartis Investigative Site, Beersheba
Novartis Investigative Site, Eggenfelden
Novartis Investigative Site, Ciudad Obregón
Novartis Investigative Site, Tucson
Novartis Investigative Site, Montebello
Novartis Investigative Site, Fürth
Novartis Investigative Site, Highland
Novartis Investigative Site, Weiden
Novartis Investigative Site, Regensburg
Novartis Investigative Site, Berkeley
Novartis Investigative Site, Coburg
Novartis Investigative Site, Portland
Novartis Investigative Site, Bellevue
Novartis Investigative Site, Kirkland
Novartis Investigative Site, Seattle
Novartis Investigative Site, Mount Vernon
Novartis Investigative Site, Sequim
Novartis Investigative Site, Tacoma
Novartis Investigative Site, Wenatchee
Novartis Investigative Site, Anchorage
Novartis Investigative Site, Ivanovo
Novartis Investigative Site, Arkhangelsk
Novartis Investigative Site, Saint Petersburg
Novartis Investigative Site, Saint Petersburg
Novartis Investigative Site, Stavropol
Novartis Investigative Site, Ryazan
Novartis Investigative Site, Lipetsk
Novartis Investigative Site, Pune
Novartis Investigative Site, Kazan'
Novartis Investigative Site, Nagpur
Novartis Investigative Site, Ufa
Novartis Investigative Site, Bangalore
Novartis Investigative Site, Kirov
Novartis Investigative Site, Greenwich
Novartis Investigative Site, Southington
Novartis Investigative Site, Stamford
Novartis Investigative Site, Trumbull
Novartis Investigative Site, Waterbury
Novartis Investigative Site, Denville
Novartis Investigative Site, Parsippany
Novartis Investigative Site, Pittsburgh
Novartis Investigative Site, Capital Federal
Novartis Investigative Site, Capital Federal
Novartis Investigative Site, Ciudad Autonoma de Buenos Aires
Novartis Investigative Site, La Plata
Novartis Investigative Site, Cipolletti
Novartis Investigative Site, Viedma
Novartis Investigative Site, Rosario
Novartis Investigative Site, Edmonton
Novartis Investigative Site, Kelowna
Novartis Investigative Site, Surrey
Novartis Investigative Site, Vancouver
Novartis Investigative Site, Victoria
Novartis Investigative Site, Winnipeg
Novartis Investigative Site, Moncton
Novartis Investigative Site, Saint John
Novartis Investigative Site, Barrie
Novartis Investigative Site, Greater Sudbury
Novartis Investigative Site, Hamilton
Novartis Investigative Site, Kingston
Novartis Investigative Site, London
Novartis Investigative Site, Newmarket
Novartis Investigative Site, Ottawa
Novartis Investigative Site, Sault Ste. Marie
Novartis Investigative Site, St. Catharines
Novartis Investigative Site, Thunder Bay
Novartis Investigative Site, Charlottetown
Novartis Investigative Site, Montreal
Novartis Investigative Site, Montreal
Novartis Investigative Site, Montreal
Novartis Investigative Site, Québec
Novartis Investigative Site, Regina
Novartis Investigative Site, Saskatoon
Novartis Investigative Site, Dresden
Novartis Investigative Site, Halle
Novartis Investigative Site, Rome
Novartis Investigative Site, Sora (FR)
Novartis Investigative Site, Sassari
Novartis Investigative Site, Aichi
Novartis Investigative Site, Chiba
Novartis Investigative Site, Ehime
Novartis Investigative Site, Kagoshima
Novartis Investigative Site, Kanagawa
Novartis Investigative Site, Osaka
Novartis Investigative Site, Osaka
Novartis Investigative Site, Saitama
Novartis Investigative Site, Saitama
Novartis Investigative Site, Shizuoka
Novartis Investigative Site, Tokyo
Novartis Investigative Site, Tokyo
Novartis Investigative Site, Mexico City
Novartis Investigative Site, Amsterdam
Novartis Investigative Site, Delft
Novartis Investigative Site, Dordrecht
Novartis Investigative Site, Maastricht
Novartis Investigative Site, Gdansk
Novartis Investigative Site, Lodz
Novartis Investigative Site, Olsztyn
Novartis Investigative Site, Olsztyn
Novartis Investigative Site, Płock
Novartis Investigative Site, Rzeszów
Novartis Investigative Site, Warsaw
Novartis Investigative Site, Warsaw
Novartis Investigative Site, Moscow
Novartis Investigative Site, Gyeonggi-do
Novartis Investigative Site, Seoul
Novartis Investigative Site, Seoul
Novartis Investigative Site, Seoul
Novartis Investigative Site, Songpa-gu, Seoul
Novartis Investigative Site, Alicante
Novartis Investigative Site, Badalona
Novartis Investigative Site, Barcelona
Novartis Investigative Site, Elche
Novartis Investigative Site, Bournemouth
Novartis Investigative Site, Brighton
Novartis Investigative Site, Chelmsford
Novartis Investigative Site, Cheltenham
Novartis Investigative Site, Colchester
Novartis Investigative Site, Cottingham, Hull
Novartis Investigative Site, Derby
Novartis Investigative Site, Edmonton
Novartis Investigative Site, Guildford
Novartis Investigative Site, Harrogate
Novartis Investigative Site, Huddersfield
Novartis Investigative Site, London
Novartis Investigative Site, Newcastle upon Tyne
Novartis Investigative Site, Norwich
Novartis Investigative Site, Nottingham
Novartis Investigative Site, Oxford
Novartis Investigative Site, Poole, Dorset
Novartis Investigative Site, Sheffield
Novartis Investigative Site, Shrewsbury
Novartis Investigative Site, Sutton
Novartis Investigative Site, Whitchurch, Cardiff
Novartis Investigative Site, York
Lead Sponsor
Collaborators (1)
NCIC Clinical Trials Group
NETWORK
Novartis Pharmaceuticals
INDUSTRY