Combination Chemotherapy, Radiation Therapy, and Sargramostim Before and After Surgery in Treating Patients With Soft Tissue Sarcoma That Can Be Removed By Surgery

PHASE2CompletedINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

August 31, 2001

Primary Completion Date

November 30, 2006

Conditions
Metastatic CancerSarcoma
Interventions
BIOLOGICAL

aerosol sargramostim

BIOLOGICAL

sargramostim

DRUG

cisplatin

DRUG

doxorubicin hydrochloride

DRUG

ifosfamide

DRUG

mitomycin C

OTHER

flow cytometry

OTHER

immunological diagnostic method

OTHER

laboratory biomarker analysis

PROCEDURE

adjuvant therapy

PROCEDURE

multimodality therapy

PROCEDURE

neoadjuvant therapy

PROCEDURE

therapeutic conventional surgery

RADIATION

intraoperative radiation therapy

RADIATION

selective external radiation therapy

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Mayo Clinic

OTHER