18
Participants
Start Date
October 9, 2006
Primary Completion Date
September 6, 2016
Study Completion Date
September 6, 2016
high performance liquid chromatography
Performed on serial blood samples from 0 to 168 hours and daily X5 days 24 hour urine samples
pharmacological study
Serial blood samples from 0 to 168 hours and daily X5 days 24 hour urine samples
radionuclide imaging
1-3 hours, 1 day, 2 days, 3-5 days and 6-7 days post Y-90 anti-CEA antibody infusion
single photon emission computed tomography
2 days and 3-5 days post antibody infusion
yttrium Y 90 DOTA anti-CEA monoclonal antibody M5A
Dose escalation from 12 mCi/m2 through 18 mCi/m2 increasing by 2 mCi/m2 with each escalation
City of Hope Comprehensive Cancer Center, Duarte
National Cancer Institute (NCI)
NIH
City of Hope Medical Center
OTHER