Study of AAV-GAD Gene Transfer Into the Subthalamic Nucleus for Parkinson's Disease

PHASE2TerminatedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

August 31, 2008

Primary Completion Date

December 31, 2010

Conditions
Parkinson's Disease
Interventions
GENETIC

Bilateral surgical infusion of AAV-GAD into the subthalamic nucleus

One-time bilateral administration of rAAV-GAD at 1X10\^12 vector genomes in 35 uL.

Trial Locations (7)

14642

University of Rochester, Rochester

27157

Wake Forest University Health Science Center, Winston-Salem

43210

The Ohio State University, Columbus

48034

Henry Ford Health Systems - Franklin Pointe Medical, Southfield

80045

University of Colorado, Aurora

94305-5401

Stanford University, Stanford

02114

Massachusetts General Hospital, Boston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Neurologix, Inc.

INDUSTRY