High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma

PHASE2TerminatedINTERVENTIONAL
Enrollment

7

Participants

Timeline

Start Date

October 31, 2008

Primary Completion Date

March 31, 2009

Study Completion Date

April 30, 2009

Conditions
Osteosarcoma
Interventions
DRUG

glucarpidase

IV dose based on weight, two doses given for 5 minutes, 24 hours apart

DRUG

leucovorin

IV or po given every 6 hours

Sponsors
All Listed Sponsors
collaborator

M.D. Anderson Cancer Center

OTHER

lead

BTG International Inc.

OTHER