Effect of Different Iloprost Doses on Symptoms in Systemic Sclerosis

PHASE2TerminatedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

September 30, 1997

Primary Completion Date

December 31, 2003

Study Completion Date

December 31, 2007

Conditions
Systemic Sclerosis
Interventions
DRUG

iloprost

0.5-2 ng/kg x min for 6hours a day for 21 consecutive days

DRUG

iloprost low dose

0.5 ng/kg x min over 6 h per day for 21 consecutive days

DRUG

iloprost therapy up to 2 ng/kg x min

starting therapy at doses of 0.5 ng/kg x min, increase the dose every two days for 0.5 ng/kg x min up to the maximally tolerated dose or to 2 ng/kg x min

Trial Locations (1)

10117

Charrité Universitätsmedizin, Berlin

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Schering-Plough

INDUSTRY

lead

Charite University, Berlin, Germany

OTHER