Avastin, Fluorouracil, Doxorubicin and Streptozocin in Locally Advanced and Metastatic Pancreatic Endocrine Tumors

PHASE2TerminatedINTERVENTIONAL
Enrollment

1

Participants

Timeline

Start Date

August 31, 2007

Primary Completion Date

March 31, 2008

Study Completion Date

March 31, 2008

Conditions
Pancreatic Cancer
Interventions
DRUG

Avastin

Every 28 Days: Avastin 5mg/kg iv days 1 and 15

DRUG

Fluorouracil

Every 28 Days: Fluorouracil 400mg/m\^2 iv bolus daily days 1-5

DRUG

Doxorubicin

Every 28 Days: Doxorubicin 40mg/m\^2 iv bolus day 1

DRUG

Streptozocin

Every 28 Days: Streptozocin 400mg/m2 iv bolus daily days 1-5

DRUG

Dexamethasone

Premedication: Dexamethasone 20mg intravenously days 1-5

DRUG

Ondansetron

Premedication: Ondansetron 16mg intravenously days 1-5

Trial Locations (1)

33612

H. Lee Moffitt Cancer Center and Research Institute, Tampa

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

H. Lee Moffitt Cancer Center and Research Institute

OTHER