Photopheresis for the Treatment of Acute Graft Versus Host Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

81

Participants

Timeline

Start Date

January 31, 2008

Primary Completion Date

January 31, 2016

Study Completion Date

January 31, 2016

Conditions
Graft Versus Host Disease
Interventions
PROCEDURE

Photopheresis

8-9 photopheresis treatments weekly for days 1-14, 6 treatments weekly from days 15-28, and after that 2 treatments weekly until day 60. After day 60, your doctor will decide whether ECP is worth continuing, and the frequency of treatments.

DRUG

Methylprednisolone

2 mg/kg daily with a taper to no less than 1 mg/kg/day by day 14, followed by a tapering schedule according to the suggested guidelines.

Trial Locations (1)

77030

University of Texas MD Anderson Cancer Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Mallinckrodt

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER