Varenicline and Nicotine Interactions in Humans (VA)

Varenicline (1 mg per day) given for 4 days prior to laboratory session

Sugar Pill

IV Nicotine given during the laboratory session following 4 days of exposure to the study medication (varenicline or placebo). This nicotine was given during each laboratory session which followed the 4 days of exposure to either placebo then varenicline or varenicline then placebo.