Effectiveness of Enhanced Counseling and Observed Therapy on Antiretroviral Adherence in People With HIV

NACompletedINTERVENTIONAL
Enrollment

252

Participants

Timeline

Start Date

December 31, 2004

Primary Completion Date

August 31, 2009

Study Completion Date

August 31, 2009

Conditions
HIV InfectionsAcquired Immunodeficiency Syndrome
Interventions
BEHAVIORAL

Motivational interviewing with cognitive behavioral therapy

Counseling sessions are completed face-to-face or by telephone at baseline and Weeks 1, 2, 4, 6, 9, 11, 15, 19, and 23. Counselors are trained in motivational interview technique and focus on ART medication adherence.

BEHAVIORAL

Modified directly observed therapy

From baseline to Week 16, Monday through Friday, study staff meet the participants daily to observe one dose of their ART and to leave with the participants all other doses needed until the next observed dose. The frequency of observed doses begins to taper at Week 17 through to Week 24.

Trial Locations (4)

64108

Truman Medical Center ID Clinic, Kansas City

64110

Kansas City Free Health Clinic, Kansas City

66160

Kansas University Medical Center ID Clinic, Kansas City

641128

Kansas City Veterans Administration Medical Center, Kansas City

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

University of Missouri, Kansas City

OTHER

NCT00602758 - Effectiveness of Enhanced Counseling and Observed Therapy on Antiretroviral Adherence in People With HIV | Biotech Hunter | Biotech Hunter