Perioperative Pain Control With Celecoxib (Celebrex) in Total Knee Arthroplasty

PHASE4CompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

September 30, 2006

Primary Completion Date

August 31, 2009

Study Completion Date

August 31, 2009

Conditions
Osteoarthritis
Interventions
DRUG

Celecoxib (Celebrex)

The study group received 400mg oral celecoxib about 1 hr prior to surgery, and 200mg every 12 hrs, along with PCA morphine, over the first five post-operative days. The control group received placebo, along with PCA morphine over the same postoperative period. All patients received Acetaminophen 500mg qid for pain control.

Trial Locations (1)

Unknown

Ching-Chuan Jiang, Taipei

All Listed Sponsors
lead

National Taiwan University Hospital

OTHER

NCT00598234 - Perioperative Pain Control With Celecoxib (Celebrex) in Total Knee Arthroplasty | Biotech Hunter | Biotech Hunter