Preoperative Gabapentin for Acute and Chronic Post-thoracotomy Analgesia

NACompletedINTERVENTIONAL
Enrollment

146

Participants

Timeline

Start Date

June 30, 2007

Primary Completion Date

January 31, 2010

Study Completion Date

March 31, 2010

Conditions
Pain
Interventions
DRUG

Gabapentin

gabapentin 600 mg orally within 2 hours preoperatively, epidural infusion of 0.075% bupivacaine with 10 mcg/ml of hydromorphone at 6 ml/hour, fentanyl intravenous patient controlled analgesia at 10 mcg every 10 minutes as needed with a 200 mcg 4 hour lockout, oral acetaminophen 650 mg orally every 6 hours as needed for pain, intravenous ketorolac 15 mg every 6 hours as needed for pain.

DRUG

Diphenhydramine

Diphenhydramine 12.5 mg orally within 2 hours preoperatively, epidural infusion of 0.075% bupivacaine with 10 mcg/ml of hydromorphone at 6 ml/hour, fentanyl intravenous patient controlled analgesia at 10 mcg every 10 minutes as needed with a 200 mcg 4 hour lockout, oral acetaminophen 650 mg orally every 6 hours as needed for pain, intravenous ketorolac 15 mg every 6 hours as needed for pain.

Trial Locations (1)

55905

Mayo Clinic, Rochester

All Listed Sponsors
lead

Michelle Kinney

OTHER

NCT00588159 - Preoperative Gabapentin for Acute and Chronic Post-thoracotomy Analgesia | Biotech Hunter | Biotech Hunter