Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMI

PHASE2CompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

May 31, 2005

Primary Completion Date

January 31, 2012

Study Completion Date

January 31, 2012

Conditions
Myocardial Reperfusion Injury
Interventions
DRUG

BQ-123

BQ-123 is a cyclic peptide consisting of five amino acids. BQ-123 will be infused at 300 nmol/min for 20 minutes prior to percutaneous coronary intervention (PCI).

DRUG

Placebo

Subjects randomized to the placebo arm will receive a placebo infusion (saline) for 20 minutes prior to PCI.

Trial Locations (1)

55905

Mayo Clinic, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER