Memantine Treatment in Fragile X-Associated Tremor/Ataxia Syndrome

NACompletedINTERVENTIONAL
Enrollment

94

Participants

Timeline

Start Date

September 30, 2007

Primary Completion Date

September 30, 2012

Study Completion Date

September 30, 2012

Conditions
Fragile X-Associated Tremor/Ataxia SyndromeFragile X Premutation Carriers
Interventions
DRUG

Memantine

Week 1: Take 5mg tab every morning. Week 2: Take 5mg tab every morning and evening. Week 3: Take 10mg tab in the morning and 5 mg in the evening. Week 4: Take 10 mg tab in the morning and evening, and remain on this dose through the remainder of the study.

DRUG

Placebo

Week 1: Take 5mg tab every morning. Week 2: Take 5mg tab every morning and evening. Week 3: Take 10mg tab in the morning and 5 mg in the evening. Week 4: Take 10 mg tab in the morning and evening, and remain on this dose through the remainder of the study.

Trial Locations (2)

80045

University of Colorado Health Sciences Center, Aurora

95817

UC Davis MIND Institute, Sacramento

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

collaborator

Forest Laboratories

INDUSTRY

lead

University of California, Davis

OTHER