NCT00580853 - The Effect of Varenicline (Chantix) and Bupropion (Zyban) on Smoking Lapse Behavior | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

April 30, 2007

Primary Completion Date

October 31, 2016

Study Completion Date

October 31, 2016

Conditions

Smoking Lapse Behavior

Interventions

DRUG

varenicline

2mg/day, with 1-week lead-in medication period The starting dose is 0.5 mg/day for days 1-2, followed by 0.5mg twice daily for days 3-5 and then 1mg twice daily for days 4-7. 1mg administered during laboratory session (day 8).

DRUG

bupropion

300mg/day, with 1-week lead-in medication period The starting dose is 150mg/day for days 1-3, 300mg/day for days 4-7. 300mg administered during laboratory session (day 8).

DRUG

Placebo

Trial Locations (1)

06519

Yale Center for Clinical Investigation, Yale University, New Haven

All Listed Sponsors

collaborator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

lead

Yale University

OTHER